Pardis Sabeti

Pardis Sabeti is an assistant professor in Harvard University’s Center for Systems Biology and Department of Organismic and Evolutionary Biology. She is also an associate member of the Broad Institute. Her work focuses on determining the effects of natural selection on the human genome and the genomes of other organisms and understanding the mechanisms of evolutionary adaptation in humans as well as pathogens. Her laboratory is pursuing three lines of research: (1) developing analytical methods to detect and investigate natural selection in the genome of humans and other species, (2) pursuing signals of natural selection to identify their underlying functional trait (e.g. hair, sweat, and teeth development, and resistance to Lassa fever virus) and the mechanism of evolution, and (3) examining signals of natural selection in the pathogen Plasmodium falciparum malaria to understand how it rapidly evolves, and studying its genetic diversity to guide long term intervention strategies.

Learn more about research in the Sabeti laboratory here.