Mycobacterium tuberculosis Database
Mycobacterium tuberculosis causes 8-9 million cases of infection, and 1.5 million deaths every year. These numbers are on the rise globally, especially in Africa, Eastern Europe and the former Soviet Union. Part of the problem in treating TB is the appearance of drug resistant TB strains, including strains with multiple drug resistance (MDR) and, more recently, strains with extensive drug resistance (XDR), which are much more difficult to treat.
In this project, we are performing sequencing and comparative analysis of multiple patient isolates with varying clinical phenotypes and disease epidemiology. Our goal is to have a better understanding of the molecular basis of fundamental clinical phenotypes such as TB transmission and drug resistance.
| Newly generated Solexa/ABI Assemblies | |
| Solexa/ABI sequence for three M. tuberculosis KZN strains, isolated from KwaZulu-Natal (KZN), South Africa, are now available for download. |
ToolsBLAST Search: Find similarities to other sequences Feature Search: Search and view annotated features on the sequence Browse Regions: Retrieve DNA, find clones, and graphically view sequence regions Gene Index: Find genes by a variety of methods Genome Statistics:View basic statistics about genome size, gene density, etc Download Data: Download sequence, genes, markers, and other genome data InformationContact Us:Addresses for contacting the Broad Institute Related Links:Links to sites related to the Mycobacterium tuberculosis genome project |
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