Community Annotation Project

The goals of the Methanosarcina acetivorans sequencing and annotation project were:
  • To provide a rich and accurate genomic resource for the scientific community

  • To produce a published analysis of the genome that sheds light on the biology of Methanosarcina acetivorans and spurs further research into this and related organisms
In order to produce high quality whole-genome annotation and analysis, we created a collaborative process involving dozens of experts around the country. We would like to thank these participants who generously donated their time and expertise to this project.

The primary goals of the Community Annotation Project (CAP) were:

  • To verify and improve the accuracy and consistency of the genome annotation.

  • To construct a working model of the important biochemical pathways and cellular processes of Methanosarcina acetivorans based on annotated genes and other features.

  • To analyze and interpret the genome for insights and discoveries.
The community annotation process culminated in a two day Genome Analysis Meeting at the Whitehead Institute where the results of all analyses were shared and discussed, and a draft of a whole-genome analysis paper was prepared.

CAP annotations

You can view all the annotations submitted by CAP participants using the link below. CAP annotations are also available from the "Gene Detail" page for each gene.

CAP participants

Name Organization Email
Barber, Robert University of Wisconsin-Parkside robert.barber@uwp.edu
Cann, Isaac New England Biolabs cann@neb.com
Conway de Macario, Everly NYS Dept. of Health everlym@wadsworth.org
Ferry, James Penn State JGF3@psu.edu
Gottschalk, Gerhard Goettingen ggottsc@gwdg.de
Graham, David Virginia Tech degraham@vt.edu
Grahame, David Uniformed Services University dgrahame@usuhs.mil
Gunsalus, Robert UCLA robg@microbio.ucla.edu
Hedderich, Reiner Max-Plank hedderic@mailer.uni-marburg.de
Ingram-Smith, Cheryl Penn State University cji2@psu.edu
Jarrell, Ken Queens University, Kinston Ontario jarrellk@post.queensu.ca
Jing, Holly Harvard University jing@sprsgi.med.harvard.edu
Krzycki, Joseph Ohio State University krzycki.1@osu.edu
Leigh, John Univeristy of Washington leighj@u.washington.edu
Macario, Alberto NYS Dept. of Health macario@wadsworth.org
Metcalf, William University of Illinois b-metcalf@life.uiuc.edu
Mukhopadhyay, Biswarup UIUC - postdoc for Wolfe biswarup@life.uiuc.edu
Olsen, Gary Univeristy of Illinois gary@phylo.life.uiuc.edu
Paulsen, Ian TIGR ipaulsen@tigr.org
Reeve, John Ohio State University reeve.2@osu.edu
Saier, Milt UCSD msaier@ucsd.edu
Smith, Kerry Penn State University kss9@psu.edu
Sowers, Kevin University of Maryland Biotechnology Institute Sowers@umbi.umd.edu
Swanson, Ron Syrrx,Inc. ron.swanson@syrrx.com
Tabita, Robert Ohio State University Tabita.1@osu.edu
Thaur, Rolf MPI (Marburg) thauer@mailer.uni-marburg.de
White, Robert (Bob) Virginia Tech rhwhite@vt.edu
Whitman, William B University of Georgia whitman@arches.uga.edu
Zinder, Stephen Cornell University shz1@cornell.edu