Paola Arlotta is an associate member of the Stanley Center for Psychiatric Research at the Broad Institute. A leading neuroscientist, Arlotta is interested in understanding the molecular underpinnings that govern the birth, differentiation, and assembly into working circuitry of cells in the nervous system—particularly corticospinal neurons, a type of nerve cell linked to ALS (Lou Gehrig's disease), Hereditary Spastic Paraplegia (HSP), Primary Lateral Sclerosis (PLS), and that is permanently damaged in spinal cord injury. Arlotta is working to harness the genetic programs that control the differentiation of corticospinal neurons to develop novel strategies for cell replacement therapy in neurodegenerative diseases.
In addition to her work at the Broad, Arlotta is an Associate Professor of Stem Cell and Regenerative Biology at Harvard University. She is also a principal faculty member at the Harvard Stem Cell Institute.
Arlotta received her M.S. in Biochemistry from the University of Trieste, Italy and her Ph.D. in Molecular Biology from the University of Portsmouth in the UK. She subsequently completed her postdoctoral training in Neuroscience at Harvard Medical School.
Photo courtesy of B. D. Colen, Harvard UniversityLast updated date: June 2015