Broad Institute Chemical Biology Program
  Instruments
  Library
  Screening

Facilities: Instruments

Automated Reaction Station:  

Chemspeed ASW2000

   

Berger SFC Supercritical liquid chromatograph
with Waters ZQ Mass Detector

   

Liquid chromatography with Waters ZQ Mass Detector

   

Autochem Miniblock

Analytical Intruments & Robotics

Reverse Phase liquid chromatography with ThermoFinnigan AQA Mass Spectrometer

   

Tango Liquid Handling System

A more advancced liquid handling robot cpable of transferring the compounds from teh bead plates to intermediate plates to automate the formatting process

http://www.matrixtechcorp.com/LH/Tango.asp

   

Genevac HT-12

An ultra high throughput evaporator

http://www.genevac.com/products/ht12.html

   

ICSO CombiFlash Companion MPLC

Medium Pressure liquid Chromatography capable of purifying up to 10g of individual compound

http://www.axel-semrau.de/produktdetail.php4?nr=184~lastgrp=34

   

Analytical HPLC

For analysis of UV-active compounds, useful for monitoring reactions

http://www.waters.com/WatersDivision/ContentD.asp?watersit=CSAN-5MBNFT

   

Preparative HPLC

For purification of compounds on an analytical or preparative scale

http://www.waters.com/WatersDivision/contentd.asp?ref=JDRS-5LG4KD

   

LCMS-I

For compund identification purity assessment, and quantitation.

http://www.waters.com/WatersDivision/ContentD.asp?ref=JDRS-5KUPMJ

   

LCMS-II

For compund identification purity assessment, and quantitation.

http://www.waters.com/WatersDivision/ContentD.asp?ref=JDRS-5KUPMJ

   

IVEK HF-Pyridine Dispenser

A liquid handling robot capable of dispensing HF-pyridine cleavage solution into plates (cleavage station) to automate the process of cleaving compunds from their beads

http://www.ivek.com/products.html

   

Robbins Scientific Hydra-384 Microdispenser

A liquid handling robot capable of dispensing chemical solutions (such as tag-cleavage cocktail) to automate the process of cleaving tags from beads
http://www.matrixtechcorp.com/LH/Hydra.asp

   

Agilent 6890 MECD-GC

With electron-capture detector, used for analysis of the electrophoric tags used for library encoding

http://www.chem.agilent.com

 

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