Center for Genotyping and Analysis

Publications

The Broad Institute Center for Genotyping and Analysis, and its founding grant (U54 RR020278) from the National Center for Research Resources, have through their laboratory and analytic resources for SNP genotyping enabled the generation of data and results supporting the following scientific publications.

Authors listed in green received a genotyping subsidy from the NCRR for some or all of the work described in the publication.

Search PubMed for RR020278 [Grant Number]

2008

Anttila, V., Nyholt, D.R., Kallela, M., Artto, V., Vepsalainen, S., Jakkula, E., Wennerstrom, A., Tikka-Kleemola, P., Kaunisto, M.A., Hamalainen, E., Widen, E., Terwilliger, J., Merikangas, K., Montgomery, G.W., Martin, N.G., Daly, M., Kaprio, J., Peltonen, L., Farkkila, M., Wessman, M., and Palotie, A. (2008). Consistently replicating locus linked to migraine on 10q22-q23. Am J Hum Genet 82, 1051-1063.

Gayan, J., Brocklebank, D., Andresen, J.M., Alkorta-Aranburu, G., Zameel Cader, M., Roberts, S.A., Cherny, S.S., Wexler, N.S., Cardon, L.R., and Housman, D.E. (2008). Genomewide linkage scan reveals novel loci modifying age of onset of Huntington's disease in the Venezuelan HD kindreds. Genet Epidemiol. 32, 445-53.

Graham, D.S., Graham, R.R., Manku, H., Wong, A.K., Whittaker, J.C., Gaffney, P.M., Moser, K.L., Rioux, J.D., Altshuler, D., Behrens, T.W., and Vyse, T.J. (2008). Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus. Nat Genet 40, 83-89.

Graham, D.S., Vyse, T.J., Fortin, P.R., Montpetit, A., Cai, Y.C., Lim, S., McKenzie, T., Farwell, L., Rhodes, B., Chad, L., Hudson, T.J., Sharpe, A., Terhorst, C., Greenwood, C.M., Wither, J., and Rioux, J.D. (2008). Association of LY9 in UK and Canadian SLE families. Genes Immun 9, 93-102.

Limdi, N.A., Arnett, D.K., Goldstein, J.A., Beasley, T.M., McGwin, G., Adler, B.K., and Acton, R.T. (2008). Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans. Pharmacogenomics 9, 511-526.

Limdi, N., McGwin, G., Goldstein, J., Beasley, T., Arnett, D., Adler, B., Baird, M., and Acton, R. (2008). Influence of CYP2C9 and VKORC1 1173C/T Genotype on the Risk of Hemorrhagic Complications in African-American and European-American Patients on Warfarin. Mol Ther 83, 312-321.

Matera, I., Watkins-Chow, D.E., Loftus, S.K., Hou, L., Incao, A., Silver, D.L., Rivas, C., Elliott, E.C., Baxter, L.L., and Pavan, W.J. (2008). A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy. Hum Mol Genet.

Nath, S.K., Guthridge, J.M., Cobb, B.L., Mirel, D.B., Marion, M.C., Williams, A.H., Divers, J.D., Wang, W., Frank, S.G., Namjou, B., Gabriel, S.B., Lee, A.T., Gregersen, P.K., Behrens, T.W., Taylor, K.E., Fernando, M., Zidovetzki, R., Gaffney, P.M., Edberg, J.C., Rioux, J.D., Ojwang, J.O., James, J.A., Merrill, J.T., Gilkeson, G.S., Seldin, M.F., Yin, H., Baechler, E.C., Li, Q.Z., Wakeland, E.K., Bruner, G.R., Kaufman, K.M., Kelly, J.A., Harley, J.B., Alarcon-Riquelme, M.E., Criswell, L.A., Jacob, C.O., Kimberly, R.P., Moser, K.L., Tsao, B.P., Vyse, T.J., and Langefeld, C.D. (2008). Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 40, 204-210.

Perlis, R.H., Purcell, S., Fagerness, J., Kirby, A., Petryshen, T.L., Fan, J., and Sklar, P. (2008). Family-based association study of lithium-related and other candidate genes in bipolar disorder. Arch Gen Psychiatry 65, 53-61.

Price, A.L., Butler, J., Patterson, N., Capelli, C., Pascali, V.L., Scarnicci, F., Ruiz-Linares, A., Groop, L., Saetta, A.A., Korkolopoulou, P., Seligsohn, U., Waliszewska, A., Schirmer, C., Ardlie, K., Ramos, A., Nemesh, J., Arbeitman, L., Goldstein, D.B., Reich, D., and Hirschhorn, J.N. (2008). Discerning the Ancestry of European Americans in Genetic Association Studies. PLoS Genet 4, e236.

Ross, R.W., Oh, W.K., Xie, W., Pomerantz, M., Nakabayashi, M., Sartor, O., Taplin, M.E., Regan, M.M., Kantoff, P.W., and Freedman, M. (2008). Inherited variation in the androgen pathway is associated with the efficacy of androgen-deprivation therapy in men with prostate cancer. J Clin Oncol 26, 842-847.

Taconic | Newsroom | News | 2008 | C57BL/6 and Apoe mouse strains resumed.

2007

Fernando, M.M., Stevens, C.R., Sabeti, P.C., Walsh, E.C., McWhinnie, A.J., Shah, A., Green, T., Rioux, J.D., and Vyse, T.J. (2007). Identification of two independent risk factors for lupus within the MHC in United Kingdom families. PLoS Genet 3, e192.

Florez, J.C., Manning, A.K., Dupuis, J., McAteer, J., Irenze, K., Gianniny, L., Mirel, D.B., Fox, C.S., Cupples, L.A., and Meigs, J.B. (2007). A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets. Diabetes 56, 3063-3074.

Francis, P.J., George, S., Schultz, D.W., Rosner, B., Hamon, S., Ott, J., Weleber, R.G., Klein, M.L., and Seddon, J.M. (2007). The LOC387715 gene, smoking, body mass index, environmental associations with advanced age-related macular degeneration. Hum Hered 63, 212-218.

Hafler, D.A., Compston, A., Sawcer, S., Lander, E.S., Daly, M.J., De Jager, P.L., de Bakker, P.I., Gabriel, S.B., Mirel, D.B., Ivinson, A.J., Pericak-Vance, M.A., Gregory, S.G., Rioux, J.D., McCauley, J.L., Haines, J.L., Barcellos, L.F., Cree, B., Oksenberg, J.R., and Hauser, S.L. (2007). Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357, 851-862.

Kim, K., Lerou, P., Yabuuchi, A., Lengerke, C., Ng, K., West, J., Kirby, A., Daly, M. J., and Daley, G. Q. (2007). Histocompatible embryonic stem cells by parthenogenesis. Science 315, 482-486.

Kim, K., Ng, K., Rugg-Gunn, P.J., Shieh, J.-H., Kirak, O., Jaenisch, R., Wakayama, T., Moore, M.A., Pedersen, R.A., and Daley, G.Q. (2007). Recombination Signatures Distinguish Embryonic Stem Cells Derived by Parthenogenesis and Somatic Cell Nuclear Transfer. Cell Stem Cell 1, 346-352.

Levillayer, F., Mas, M., Levi-Acobas, F., Brahic, M., and Bureau, J.F. (2007). Interleukin 22 is a candidate gene for Tmevp3, a locus controlling Theiler's virus-induced neurological diseases. Genetics 176, 1835-1844.

Maller, J.B., Fagerness, J.A., Reynolds, R.C., Neale, B.M., Daly, M.J., and Seddon, J.M. (2007). Variation in complement factor 3 is associated with risk of age-related macular degeneration. Nat Genet 39, 1200-1201.

Manolio, T.A., Rodriguez, L.L., Brooks, L., Abecasis, G., Ballinger, D., Daly, M., Donnelly, P., Faraone, S.V., Frazer, K., Gabriel, S., Gejman, P., Guttmacher, A., Harris, E.L., Insel, T., Kelsoe, J.R., Lander, E., McCowin, N., Mailman, M.D., Nabel, E., Ostell, J., Pugh, E., Sherry, S., Sullivan, P.F., Thompson, J.F., Warram, J., Wholley, D., Milos, P.M., and Collins, F.S. (2007). New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet 39, 1045-1051.

Poirier, C., Moran, J.L., Kovanci, E., Petit, D.C., Beier, D.R., and Bishop, C.E. (2007). Three loci on mouse chromosome 5 and 10 modulate sex determination in XX Ods/+ mice. Genesis 45, 452-455.

Price, A.L., Patterson, N., Yu, F., Cox, D.R., Waliszewska, A., McDonald, G.J., Tandon, A., Schirmer, C., Neubauer, J., Bedoya, G., Duque, C., Villegas, A., Bortolini, M.C., Salzano, F.M., Gallo, C., Mazzotti, G., Tello-Ruiz, M., Riba, L., Aguilar-Salinas, C.A., Canizales-Quinteros, S., Menjivar, M., Klitz, W., Henderson, B., Haiman, C.A., Winkler, C., Tusie-Luna, T., Ruiz-Linares, A., and Reich, D. (2007). A genomewide admixture map for Latino populations. Am J Hum Genet 80, 1024-1036.

Seddon, J.M., Francis, P.J., George, S., Schultz, D.W., Rosner, B., and Klein, M.L. (2007). Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration. JAMA 297, 1793-1800.

Shaffer, J.R., Kammerer, C.M., Reich, D., McDonald, G., Patterson, N., Goodpaster, B., Bauer, D.C., Li, J., Newman, A.B., Cauley, J.A., Harris, T.B., Tylavsky, F., Ferrell, R.E., and Zmuda, J.M. (2007). Genetic markers for ancestry are correlated with body composition traits in older African Americans. Osteoporos Int 18, 733-741.

Taconic | Newsroom | 2007 | 129s6/SvEvTac Genetic Integrity Comes Clean.

2006

Li, M., Atmaca-Sonmez, P., Othman, M., Branham, K. E., Khanna, R., Wade, M. S., Li, Y., Liang, L., Zareparsi, S., Swaroop, A., and Abecasis, G. R. (2006). CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration. Nat Genet 38, 1049-1054.

Maller, J., George, S., Purcell, S., Fagerness, J., Altshuler, D., Daly, M. J., and Seddon, J. M. (2006). Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet 38, 1055-1059.  

Seddon, J. M., George, S., Rosner, B., and Klein, M. L. (2006). CFH gene variant, Y402H, and smoking, body mass index, environmental associations with advanced age-related macular degeneration. Hum Hered 61, 157-165.  

 

Contact

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