Personal neoantigen cancer vaccines: The momentum builds.

Oncoimmunology
Authors
Abstract

Neoantigen-based cancer vaccines designed to target the unique immunogenic mutations arising in each patient's tumor are breathing new life into a struggling approach. Data continue to demonstrate the importance of neoantigens in immune control of cancer. Despite manufacturing complexity, outstanding questions and desired further improvements, neoantigen vaccines are currently undergoing clinical evaluation.

Year of Publication
2014
Journal
Oncoimmunology
Volume
3
Pages
e29311
Date Published
2014
ISSN
2162-4011
DOI
10.4161/onci.29311
PubMed ID
25101225
PubMed Central ID
PMC4121338
Links